Rituximab-Associated Neutropenia
نویسندگان
چکیده
منابع مشابه
Rituximab-associated neutropenia.
Several recent studies have reported the phenomenon of late-onset neutropenia occurring usually several months following the administration of rituximab or rituximab-based therapies. While it appears that late-onset neutropenia is usually not clinically significant and is self-limited, it is important to recognize its existence given the expanding use of rituximab in both hematologic and nonhem...
متن کاملRituximab associated neutropenia: Description of three cases and an insight into the underlying pathogenesis
BACKGROUND To describe Rituximab associated neutropenia (RAN), and to explore its underlying mechanism. CASE REPORT We describe three patients with RAN. The effect of patient's plasma on colony forming unit, Granulocyte-Monocyte (CFU-GM) was measured by the addition of plasma to the culture of a healthy bone-marrow. Repeated tests were performed after recovery of white count. In the leukopeni...
متن کاملEarly onset neutropenia after rituximab in lupus nephritis.
E-mail: [email protected] References 1. SILVE C: Hereditary hypophosphatasia and hyperphosphatasia. Curr Opin Rheumatol 1994; 6: 3369. 2. GRAEPEL P, BENTLEY P, FRITZ H, MIYAMOTO M, SLATER SR: Reproduction toxicity studies with pamidronate. Arzneimittelforschungnn 1992; 42: 654-67. 3. BLACK AJ, TOPPING J, DURHAM B, FARQUHARSON RG, FRASER WD: A detailed assessment of alterations in bone turno...
متن کاملDelayed-onset and long-lasting severe neutropenia due to rituximab.
BACKGROUND Rituximab, a monoclonal antibody, is effective in CD20-positive B-cell lymphoma and is now widely used either as a single agent or in combination with chemotherapy. The antibody's toxicity is generally mild and transient. There are reports of protracted neutropenia in patients treated with rituximab. CASE REPORT We report on a patient with Burkitt's lymphoma treated with the hyper-...
متن کاملneutropenia associated with x-linked agammaglobulinemia
x-linked agammaglobulinemia (xla) is a hereditary immunodeficiency, characterized by an early onset of recurrent bacterial infections, hypogammaglobulinemia and markedly reduced b lymphocytes number. in order to determine the association of neutropenia among iranian patients with xla, hospital records of 30 patients with confirmed xla in children medical center hospital, were reviewed. eight ou...
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ژورنال
عنوان ژورنال: Seminars in Hematology
سال: 2010
ISSN: 0037-1963
DOI: 10.1053/j.seminhematol.2010.01.009